Land for sale in Anderson County, Tennessee, recently totaled around $98 million and almost 1,000 acres. Anderson County ranks 32nd out of 95 counties in Tennessee for the combined amount of land currently advertised for sale. Among cities in Anderson County with land and rural real estate for sale, Clinton had the most land for sale. Manufacturing and related services are the largest economic sectors in Anderson County. Anderson County is the 66th biggest county (344 square miles) in Tennessee. It's located in the Eastern Tennessee region of the state.