The value of all land for sale in Chatham County recently was nearly $506 million, representing a combined 5,822 acres of land for sale in Chatham County. Chatham County ranks 28th in the Tar Heel State for the combined amount of land currently advertised for sale. Among cities in Chatham County with land for sale, Pittsboro had the most land for sale. Chatham County is North Carolina's 20th largest county (708 square miles). It's located in the Piedmont North Carolina region of North Carolina.