Land for sale in Cherokee County, Iowa, recently totaled around $11 million and around 1,000 acres. Cherokee County ranks 82nd in the Hawkeye State for the combined amount of land currently advertised for sale. Among cities in Cherokee County with ranches, farms, hunting land and other rural land and acreage for sale, Cherokee featured the most land for sale. Cherokee County is the 40th largest county (577 square miles) in Iowa. It's located in the Western Iowa region of the state.