A total of 1,000 acres were listed for sale in Cherokee County recently; the value of all Cherokee County ranches, farms, hunting land and other rural land and acreage for sale was almost $11 million. Cherokee County ranks 86th in the Cyclone State for the combined amount of land currently advertised for sale. Cherokee had the most land for sale. Cherokee County is the 40th largest county (577 square miles) in Iowa. It's located in the Western Iowa region of the state.