Land for sale in Cheyenne County, Colorado, recently totaled around $6 million and almost 4,000 acres. Cheyenne County ranks 63rd in the state for the combined amount of land currently advertised for sale. Of all land for sale in Cheyenne County, Cheyenne Wells featured the most land for sale. Its economy is defined as agricultural, with 345 farms recorded in the county during the most recent U.S. Census. Farming activities in Cheyenne County generate annual revenues of $8 million, most of which is from crops. Cheyenne County is the 25th largest county (1,781 square miles) in Colorado. It's located in the Northeast Colorado region of the state.