A total of approximately 2,000 acres were listed for sale in Clay County recently; the value of all Clay County farmsand rural real estate for sale was $177 million. Clay County ranks 30th out of 67 counties in Florida for the combined amount of land currently advertised for sale. Of all locations in Clay County with farms, rural land, hunting land and other land for sale, Middleburg featured the most land for sale. Clay County is the 48th largest county (643 square miles) in Florida. It's located in the Northeast Florida region of the state.