A total of almost 1,000 acres were listed for sale in Clay County recently, representing a total value of approximately $2 million in Clay County farmsand rural real estate for sale. Clay County ranks 41st in the Mountain State for the total number of acres of land currently advertised for sale. Clay had the most land for sale. Mining and mineral extraction-related services are the main economic drivers in this part of West Virginia. Clay County is the 37th biggest county (343 square miles) in West Virginia. It's located in the Southwest West Virginia region of the state.