Land for sale in Comanche County recently totaled nearly $50 million and around 3,000 acres. Comanche County ranks 29th out of 77 counties in the Sooner State for the combined amount of land currently advertised for sale. Among cities in Comanche County with ranches, farms, hunting land and other rural land and acreage for sale, Cache featured the most land for sale. From an economic perspective, government and state-level services contribute most to Comanche County's overall GDP. Comanche County is Oklahoma's 15th largest county (1,083 square miles). It's located in the Great Plains Country Oklahoma region of Oklahoma.