Defiance County is in Northwest Ohio. Of the 88 counties in the state, 414-square-mile Defiance County ranks 67th by size. The most common type of land for sale by combined acreage in Defiance County is homesite. Browse all waterfront property for sale in Defiance County on the Land Network to find the marina, lakefront and other recreational property that meets your needs, from waterside land perfect as a retirement investment to existing residential waterfront land and property for hunting, fishing and other outdoor-recreation pursuits!