Land for sale in Fayette County, Kentucky, recently totaled around $269 million and nearly 100,000 acres. Based on the combined acreage of land and rural property for sale here, Fayette County has the most land for sale of all counties in the Bluegrass State. Among cities in Fayette County with farms, ranches, and rural real estate for sale, Lexington had the most land for sale. Government and state-level services are the main economic drivers in Fayette County. Fayette County is the 72nd biggest county (285 square miles) in Kentucky. It's located in the North Central Kentucky region of the state.