Land for sale in Mississippi's Hancock County recently totaled $175 million and nearly 5,000 acres. Hancock County ranks fourth out of 82 counties in Mississippi for the total number of acres of land currently advertised for sale. Among cities in Hancock County with farms and rural real estate for sale, Bay Saint Louis had the most land for sale. Government and state-level services are the main economic drivers in Hancock County. Hancock County is Mississippi's 44th biggest county (552 square miles). It's located in the Coastal Mississippi region of Mississippi.