Land for sale in Horry County, South Carolina, recently totaled nearly $889 million and nearly 100,000 acres. Horry County ranks first in the Palmetto State based on the combined acreage of land for sale among all the counties in the Palmetto State. Among cities in Horry County with land and rural real estate for sale, Conway featured the most land for sale. Based on its natural assets, tourism and recreation contribute significant revenue toward Horry County's overall GDP. Horry County is one of the ten largest counties in South Carolina (1,254 square miles). It's located in the Pee Dee South Carolina region of the state.