A total of around 4,000 acres were listed for sale in Missouri's Iron County recently, representing a combined around $20 million in Iron County farms, ranches, hunting land and other land for sale. Iron County ranks 77th in Missouri for the combined amount of land currently advertised for sale. Annapolis had the most land for sale. Economically speaking, Iron County's is largely dependent on mining and mineral extraction-related businesses and services. Iron County is the 66th largest county (552 square miles) in Missouri. It's located in the Southeast Missouri region of Missouri.