Land for sale in Jefferson County recently totaled approximately $283 million and approximately 8,000 acres. Jefferson County ranks second out of 67 counties in the Cotton State for the total number of acres of land currently advertised for sale. Of all locations in Jefferson County with farms, ranches, hunting land and other land for sale, Trussville featured the most land for sale. Jefferson County is one of the ten largest counties in Alabama (1,124 square miles). It's located in the Metropolitan Alabama region of Alabama.