A total of nearly 3,000 acres were listed for sale in Missouri's Jefferson County recently, representing a total value of $124 million in Jefferson County farms and ranches for sale. Jefferson County ranks 11th in the Show Me State for the total number of acres of land currently advertised for sale. Of all locations in Jefferson County with ranches, farms, hunting land and other rural land and acreage for sale, Hillsboro had the most land for sale. Jefferson County is Missouri's 41st biggest county (664 square miles). It's located in the Northeast Missouri region of Missouri.