There was a combined nearly $3 million of ranches, farms, hunting land and other rural land and acreage for sale in Jefferson County recently on Land.com. The total size of all Jefferson County farms and ranches for sale was around 1,000 acres. Jefferson County ranks 51st in the state for the total number of acres of land currently advertised for sale. Fairbury featured the most land for sale. Jefferson County is the 51st largest county (575 square miles) in Nebraska. It's located in the Southeast Nebraska region of the state.