The value of land and rural real estate for sale in Jefferson County, Nebraska, recently on Land.com was $3 million. This represents almost 1,000 acres of ranches, farms, hunting land and other rural land and acreage for sale in Jefferson County. Jefferson County ranks 57th in the state for the total number of acres of land currently advertised for sale. Among cities in Jefferson County with land for sale, Fairbury had the most land for sale. Jefferson County is the 51st biggest county (575 square miles) in Nebraska. It's located in the Southeast Nebraska region of the state.