A combined nearly 3,000 acres were listed for sale in Jefferson County recently; the value of all Jefferson County land for sale was $43 million. Jefferson County ranks 26th in the Buckeye State for the total number of acres of land currently advertised for sale. Among cities in Jefferson County with farms, ranches, hunting land and other land for sale, Wintersville had the most land for sale. Jefferson County is the 71st biggest county (410 square miles) in Ohio. It's located in the Southeast Ohio region of the state.