Land for sale in Ohio's Jefferson County recently totaled $26 million and nearly 3,000 acres. Jefferson County ranks 42nd in the Buckeye State for the combined amount of land currently advertised for sale. Of all locations in Jefferson County with farms, ranches, and rural real estate for sale, Wintersville featured the most land for sale. Jefferson County is Ohio's 71st largest county (410 square miles). It's located in the Southeast Ohio region of the state.