Land for sale in Lawrence County, Illinois, recently totaled $3 million and 1,000 acres. Lawrence County ranks 80th out of 102 counties in the Land of Lincoln for the total acreage of land currently advertised for sale. Sumner featured the most land for sale. Mining and mineral extraction-related services are the main economic drivers in this part of Illinois. Lawrence County is Illinois's 82nd biggest county (374 square miles). It's located in the Southern Illinois region of Illinois.