Lee County is in Southwest Florida. Of the 67 counties in the Everglade State, 775,918-acre Lee County ranks 15th by size. Lee County, Florida, includes 1,000 acres of beachfront homes and property for sale based on recent Land Network data. The combined market value of farmsand rural real estate for sale here was about $11 million. The average price of beachfront land for sale in Lee County was $6 million.