The combined value of land and rural real estate for sale in Missouri's Lewis County recently on Land.com was around $12 million. This represents nearly 2,000 acres of farms and ranches for sale in Lewis County. Lewis County ranks 102nd in the Ozark State for the total acreage of land currently advertised for sale. Canton had the most land for sale. Lewis County has a large agricultural economy, with 729 farms recorded in the county during the latest U.S. Census. Farming activities in Lewis County generate annual revenues of $19 million, most of which is from crops. Lewis County is the 80th largest county (510 square miles) in Missouri. It's located in the Northeast Missouri region of the state.