A total of 2,000 acres were listed for sale in Lewis County recently, representing a combined nearly $24 million in Lewis County land for sale. Lewis County ranks 43rd in the Empire State for the total number of acres of land currently advertised for sale. Of all land and rural real estate for sale in Lewis County, Natural Bridge featured the most land for sale. Based on its natural assets, Lewis County's economy is dependent on tourism and recreation. Lewis County is New York's 15th largest county (1,289 square miles). It's located in the Northern New York region of the state.