Land for sale in Lewis County recently totaled around $25 million and approximately 2,000 acres. Lewis County ranks 42nd out of 62 counties in the Empire State for the combined amount of land currently advertised for sale. Among cities in Lewis County with land and rural real estate for sale, Natural Bridge had the most land for sale. Based on its natural assets, tourism and recreation are important factors in the Lewis County economy. Lewis County is New York's 15th biggest county (1,289 square miles). It's located in the Northern New York region of New York.