The combined value of farms and ranches for sale in Madison County recently on Land.com was around $429 million. This represents approximately 7,000 acres of land and rural real estate for sale in Madison County. Madison County ranks fifth in the state for the total acreage of land currently advertised for sale. Of all land and rural real estate for sale in Madison County, Huntsville featured the most land for sale. Government and state-level services are the main economic drivers in Madison County. Madison County is Alabama's 19th largest county (812 square miles). It's located in the Mountains Alabama region of Alabama.