The value of all farms and ranches for sale in Missouri's McDonald County recently was approximately $85 million, representing a combined 6,278 acres of land for sale in McDonald County. McDonald County ranks 22nd out of 115 counties in the Ozark State for the total acreage of land currently advertised for sale. Of all locations in McDonald County with ranches, farms, hunting land and other rural land and acreage for sale, Noel had the most land for sale. Manufacturing and related services are the largest economic sectors in McDonald County. McDonald County is Missouri's 72nd largest county (539 square miles). It's located in the Southwest Missouri region of Missouri.