The total value of farmsand rural real estate for sale in McDuffie County recently on Land.com was nearly $15 million. This represents around 1,000 acres of land and rural real estate for sale in McDuffie County. McDuffie County ranks 150th out of 159 counties in Georgia for the total acreage of land currently advertised for sale. Of all locations in McDuffie County with farms, hunting land and other rural land and acreage for sale, Thomson had the most land for sale. From an economic perspective, manufacturing and related services are the main sectors in McDuffie County. McDuffie County is Georgia's 117th biggest county (266 square miles). It's located in the Historic South Georgia region of Georgia.