There was a total of nearly $15 million of farms and rural land for sale in McDuffie County, Georgia, recently on Land.com. The total acreage of all McDuffie County farms and rural real estate for sale was around 1,000 acres. McDuffie County ranks 149th in the state for the total number of acres of land currently advertised for sale. Of all farms and rural land for sale in McDuffie County, Thomson featured the most land for sale. Manufacturing and related services are the largest economic sectors in McDuffie County. McDuffie County is Georgia's 117th biggest county (266 square miles). It's located in the Historic South Georgia region of the state.