There was a total of almost $16 million of farms and rural land for sale in Georgia's McDuffie County recently on Land.com. The total of all McDuffie County farms and rural real estate for sale was around 1,000 acres. McDuffie County ranks 148th in Georgia for the total acreage of land currently advertised for sale. Among cities in McDuffie County with land for sale, Thomson had the most land for sale. From an economic perspective, manufacturing and related services are the main sectors in McDuffie County. McDuffie County is Georgia's 117th largest county (266 square miles). It's located in the Historic South Georgia region of the state.