The value of all farmsand rural real estate for sale in Mitchell County, North Carolina, recently was almost $21 million, representing a total of 784 acres of land for sale in Mitchell County. Mitchell County ranks 91st in the Tar Heel State for the total acreage of land currently advertised for sale. Among cities in Mitchell County with land and rural real estate for sale, Spruce Pine had the most land for sale. Mitchell County is the 99th biggest county (221 square miles) in North Carolina. It's located in the Mountains North Carolina region of the state.