Land for sale in Nicholas County recently totaled almost $19 million and nearly 2,000 acres. Nicholas County ranks 83rd out of 120 counties in the Bluegrass State for the total number of acres of land currently advertised for sale. Carlisle featured the most land for sale. Agriculture and farming drives the Nicholas County economy, with 570 farms recorded in the county during the U.S. Census in 2012. Farming activities in Nicholas County generate annual revenues of $2 million, most of which is from crops. Nicholas County is the 107th largest county (196 square miles) in Kentucky. It's located in the North Central Kentucky region of Kentucky.