Land for sale in Ohio County, West Virginia, recently totaled nearly $1 million and around 1,000 acres. Ohio County ranks 55th out of 55 counties in the state for the combined amount of land currently advertised for sale. Of all locations in Ohio County with farms and rural real estate for sale, Wheeling had the most land for sale. Ohio County is West Virginia's 53rd biggest county (109 square miles). It's located in the Northwest West Virginia region of West Virginia.