The total value of farms, ranches, and rural real estate for sale in Oregon County recently on Land.com was approximately $60 million. This represents almost 9,000 acres of farms, ranches, hunting land and other land for sale in Oregon County. Oregon County ranks 47th out of 115 counties in the Gateway State for the total number of acres of land currently advertised for sale. Of all locations in Oregon County with land and rural real estate for sale, Thayer had the most land for sale. Oregon County is the 14th biggest county (791 square miles) in Missouri. It's located in the Southeast Missouri region of the state.