South Texas is typically classified as the area between the San Antonio metro area and south to the Rio Grande and Gulf of Mexico. Land for sale in Refugio County, Texas, recently totaled around $46 million and almost 4,000 acres. Refugio County ranks 174th out of 254 counties in the Lone Star State for the total acreage of land currently advertised for sale. Of all farms, ranches, and rural real estate for sale in Refugio County, Refugio featured the most land for sale. Economically speaking, Refugio County's is largely dependent on mining and mineral extraction-related businesses and services. Refugio County is the 200th biggest county (818 square miles) in Texas. It's located in the Coastal Prairie South Texas region of Texas.