There was a combined almost $11 million of land for sale in Roane County recently on Land.com. The total size of all Roane County land and rural real estate for sale was nearly 3,000 acres. Roane County ranks 32nd out of 55 counties in the Mountain State for the total acreage of land currently advertised for sale. Spencer had the most land for sale. Mining and mineral extraction-related services are the main economic drivers in this part of West Virginia. Roane County is West Virginia's 18th biggest county (483 square miles). It's located in the Southwest West Virginia region of West Virginia.