The value of all farms, ranches, hunting land and other land for sale in Missouri's Saint Francois County recently was approximately $51 million, representing a combined 2,657 acres of land for sale in Saint Francois County. Saint Francois County ranks 32nd in the Gateway State for the total number of acres of land currently advertised for sale. Of all farms and ranches for sale in Saint Francois County, Bonne Terre featured the most land for sale. Saint Francois County is the 96th biggest county (454 square miles) in Missouri. It's located in the Southeast Missouri region of Missouri.