Saint Francois County is in Southeast Missouri. Of the 115 counties in the Show Me State, 290,990-acre Saint Francois County ranks 96th by size. There is nearly 1,000 acres of residential land and property for sale in Missouri's Saint Francois County based on recent Land Network data. The combined market value of farms, ranches, hunting land and other land for sale here is around $29 million. The average price of residential land for sale in Saint Francois County was $346,197. Browse all residential land and rural property for sale in Missouri to find residential land and properties that suit your lifestyle needs, from existing residential homes and estates to land ready for future residential-property development.