The value of all land and rural real estate for sale in Santa Rosa County, Florida, recently was $859 million, representing a total of 7,057 acres of land for sale in Santa Rosa County. Santa Rosa County ranks sixth in the Everglade State for the total acreage of land currently advertised for sale. Of all locations in Santa Rosa County with land and rural real estate for sale, Milton featured the most land for sale. Santa Rosa County is Florida's 17th biggest county (1,173 square miles). It's located in the Northwest Florida region of Florida.