A total of 7,000 acres were listed for sale in Santa Rosa County recently, representing a combined $753 million in Santa Rosa County land for sale. Santa Rosa County ranks seventh in Florida for the total acreage of land currently advertised for sale. Of all land and rural real estate for sale in Santa Rosa County, Milton had the most land for sale. Santa Rosa County is the 17th largest county (1,173 square miles) in Florida. It's located in the Northwest Florida region of Florida.