There was a combined around $16 million of ranches, farms, hunting land and other rural land and acreage for sale in Wapello County, Iowa, recently on Land.com. The total of all Wapello County farms, ranches, and rural real estate for sale was approximately 1,000 acres. Wapello County ranks 35th out of 99 counties in Iowa for the combined amount of land currently advertised for sale. Ottumwa featured the most land for sale. From an economic perspective, manufacturing and related services are the main sectors in Wapello County. Wapello County is the 84th largest county (436 square miles) in Iowa. It's located in the Central Iowa region of Iowa.