South Texas is typically classified as the area between the San Antonio metro area and south to the Rio Grande and Gulf of Mexico. The value of all farms, ranches, and rural real estate for sale in Zapata County, Texas, recently was almost $46 million, representing a total of 16,088 acres of land for sale in Zapata County. Zapata County ranks 224th out of 254 counties in the Lone Star State for the total acreage of land currently advertised for sale. Zapata featured the most land for sale. Economically speaking, Zapata County's is largely dependent on mining and mineral extraction-related businesses and services. Zapata County is the 69th largest county (1,058 square miles) in Texas. It's located in the Rio Grande Plains Texas region of the state.