317 CHILLICOTHE, Portsmouth, OH 45662 - Scioto County

Downtown Commercial Building with Development Potential! 317 Chillicothe Street offers a high-visibility location in the heart of historic downtown Portsmouth. This versatile property features a wide-open second floor ready for development, along with a basement offering 9-foot ceilings and over 2,500 sq ft of usable space—perfect for retail, office, or mixed-use potential. Recent upgrades include 16 tons of commercial A/C, new 3-phase electrical, updated plumbing, and new windows throughout. Large display windows, high ceilings, and an open layout offer flexibility for a variety of business uses. Located within walking distance of the courthouse, Shawnee State University, floodwall murals, and surrounded by shops, restaurants, and government buildings—this is a prime opportunity in a growing downtown district.

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