Land for sale in Calhoun County recently totaled around $3 million and almost 2,000 acres. Calhoun County ranks 49th out of 55 counties in the Mountain State for the combined amount of land currently advertised for sale. Orma featured the most land for sale. Economically speaking, Calhoun County's is largely dependent on mining and mineral extraction-related businesses and services. Calhoun County is the 46th largest county (280 square miles) in West Virginia. It's located in the Southwest West Virginia region of West Virginia.