Charles Mix County is in Great Lakes South Dakota. Of the 66 counties in the Coyote State, Charles Mix County ranks 26th in terms of size (736,151 acres). Recent listings of residential land for sale in Charles Mix County, South Dakota, totals nearly 1,000 acres and a combined market value of around $7 million. The most common type of land for sale by combined acreage in Charles Mix County is residential property. The average price of residential acreage for sale in Charles Mix County was $646,254. The economy here is largely agricultural. Browse all residential land and rural property for sale in South Dakota to find residential land and properties that suit your lifestyle needs, from existing residential homes and estates to land ready for future residential-property development.