The combined value of farms, ranches, hunting land and other land for sale in South Dakota's Brule County recently on Land.com was almost $4 million. This represents around 1,000 acres of land for sale in Brule County. Brule County ranks 31st out of 66 counties in the Coyote State for the combined amount of land currently advertised for sale. Of all locations in Brule County with land and rural real estate for sale, Chamberlain had the most land for sale. Agriculture and farming drives the Brule County economy, with 407 farms recorded in the county during the U.S. Census in 2012. Farming activities in Brule County generate annual revenues of $12 million, most of which is from crops. Brule County is the 38th biggest county (846 square miles) in South Dakota. It's located in the Great Lakes South Dakota region of the state.