Cherokee County is in Upstate South Carolina. Of the 46 counties in the Palmetto State, Cherokee County is 43rd in terms of its size (397 square miles). The total value of almost 1,000 acres of farms recently listed for sale in South Carolina's Cherokee County was almost $8 million. The average price of farms for sale in Cherokee County was $2 million. Browse all South Carolina farms for sale on the Land Network to find the farm, cattle operation, hobby farm or other farm property that's right for your future business or lifestyle needs.