Of 46 counties in the Palmetto State, Cherokee County ranks 43rd in terms of size (397 square miles). Cherokee County is in Upstate South Carolina. There is almost 1,000 acres of riverfront property for sale in South Carolina's Cherokee County based on recent Land Network data. The combined market value of farms, hunting land and other rural land and acreage for sale here is $500,000. Browse all waterfront property for sale in Cherokee County on the Land Network to find the marina, lakefront and other recreational property that meets your needs, from waterside land perfect as a retirement investment to existing residential waterfront land and property for hunting, fishing and other outdoor-recreation pursuits! The most common type of land for sale by combined acreage in Cherokee County is residential property.