Located in Low Country South Carolina, 1,133-square-mile Colleton County is one of the ten biggest counties in the state. Recent listings of residential land for sale in Colleton County, South Carolina, totals approximately 2,000 acres and a combined market value of around $101 million. The most common type of land for sale by combined acreage in Colleton County is residential property. The average price of residential acreage for sale in Colleton County was $607,139. Browse all residential land and rural property for sale in South Carolina to find residential land and properties that suit your lifestyle needs, from existing residential homes and estates to land ready for future residential-property development.