The value of all ranches, farms, hunting land and other rural land and acreage for sale in Hughes County recently was approximately $6 million, representing a total of 356 acres of land for sale in Hughes County. Hughes County ranks 34th in the Coyote State for the total acreage of land currently advertised for sale. Of all farms and ranches for sale in Hughes County, Pierre had the most land for sale. Government and state-level services are the main economic drivers in Hughes County. Hughes County is the 42nd biggest county (800 square miles) in South Dakota. It's located in the Great Lakes South Dakota region of the state.