The value of all farms, ranches, and rural real estate for sale in Hughes County recently was nearly $5 million, representing a total of 175 acres of land for sale in Hughes County. Hughes County ranks 24th out of 66 counties in the Coyote State for the total acreage of land currently advertised for sale. Of all locations in Hughes County with farms, ranches, and rural real estate for sale, Pierre had the most land for sale. Government and state-level services are the main economic drivers in Hughes County. Hughes County is South Dakota's 42nd biggest county (800 square miles). It's located in the Great Lakes South Dakota region of South Dakota.