A combined approximately 100,000 acres were listed for sale in Issaquena County recently; the value of all Issaquena County land and rural real estate for sale was almost $20 million. Issaquena County ranks 81st out of 82 counties in Mississippi for the total number of acres of land currently advertised for sale. Rolling Fork featured the most land for sale. Its economy is defined as agricultural, with 97 farms recorded in the county during the most recent U.S. Census. Farming activities in Issaquena County generate annual revenues of $1 million, 0 percent of which comes from crops and 0 percent from livestock bred in the county. Issaquena County is the 65th biggest county (441 square miles) in Mississippi. It's located in the Delta Mississippi region of Mississippi.