The value of all farmsand rural real estate for sale in Mississippi's Issaquena County recently was almost $15 million, representing a total of 13,457 acres of land for sale in Issaquena County. Issaquena County ranks 82nd based on the total amount of acres of land for sale of the 82 counties in the Magnolia State. Rolling Fork had the most land for sale. Agriculture and farming drives the Issaquena County economy, with 97 farms recorded in the county during the U.S. Census in 2012. Farming activities in Issaquena County generate annual revenues of $1 million, 0 percent of which comes from crops and 0 percent from livestock bred in the county. Issaquena County is Mississippi's 65th biggest county (441 square miles). It's located in the Delta Mississippi region of Mississippi.