The total value of land for sale in Issaquena County, Mississippi, recently on Land.com was $15 million. This represents almost 100,000 acres of land for sale in Issaquena County. Issaquena County ranks 82nd based on the total amount of acres of land for sale among the 82 counties in the Magnolia State. Among cities in Issaquena County with farms, hunting land and other rural land and acreage for sale, Rolling Fork had the most land for sale. Agriculture and farming drives the Issaquena County economy, with 97 farms recorded in the county during the U.S. Census in 2012. Farming activities in Issaquena County generate annual revenues of $1 million, 0 percent of which comes from crops and 0 percent from livestock bred in the county. Issaquena County is the 65th biggest county (441 square miles) in Mississippi. It's located in the Delta Mississippi region of the state.