A total of almost 7,000 acres were listed for sale in Issaquena County recently; the overall value of all Issaquena County farmsand rural real estate for sale was $10 million. Issaquena County ranks 82nd out of 82 counties in Mississippi for the combined amount of land currently advertised for sale. Among cities in Issaquena County with farms and rural land for sale, Fitler had the most land for sale. Agriculture and farming drives the Issaquena County economy, with 97 farms recorded in the county during the U.S. Census in 2012. Farming activities in Issaquena County generate annual revenues of $1 million, 0 percent of which comes from crops and 0 percent from livestock bred in the county. Issaquena County is Mississippi's 65th biggest county (441 square miles). It's located in the Delta Mississippi region of Mississippi.