Land for sale in Jefferson County, Oklahoma, recently totaled $22 million and 4,000 acres. Jefferson County ranks 75th out of 77 counties in Oklahoma for the total acreage of land currently advertised for sale. Waurika featured the most land for sale. Jefferson County has a large agricultural economy, with 417 farms recorded in the county during the latest U.S. Census. Farming activities in Jefferson County generate annual revenues of $2 million, the majority of which comes from livestock products. Jefferson County is Oklahoma's 45th biggest county (774 square miles). It's located in the Great Plains Country Oklahoma region of Oklahoma.