Land for sale in Mississippi's Lee County recently totaled approximately $137 million and approximately 3,000 acres. Lee County ranks eighth out of 82 counties in the Hospitality State for the total number of acres of land currently advertised for sale. Of all locations in Lee County with farms and rural real estate for sale, Tupelo had the most land for sale. From an economic perspective, manufacturing and related services are the main sectors in Lee County. Lee County is Mississippi's 61st biggest county (453 square miles). It's located in the Hills Mississippi region of Mississippi.