The value of land and rural real estate for sale in Manistee County, Michigan, recently on Land.com was nearly $99 million. This represents 4,000 acres of farms and rural land for sale in Manistee County. Manistee County ranks 28th in the Mitten State for the total acreage of land currently advertised for sale. Of all locations in Manistee County with farms, hunting land and other rural land and acreage for sale, Manistee had the most land for sale. Based on its natural assets, Manistee County's economy is dependent on tourism and recreation. Manistee County is the 26th largest county (1,280 square miles) in Michigan. It's located in the Northwest Michigan region of Michigan.