There was a total of $10 million of farms, ranches, hunting land and other land for sale in McCook County, South Dakota, recently on Land.com. The total acreage of all McCook County land for sale was approximately 1,000 acres. McCook County ranks 18th in the Coyote State for the total acreage of land currently advertised for sale. Canistota had the most land for sale. Its economy is defined as agricultural, with 568 farms recorded in the county during the most recent U.S. Census. Farming activities in McCook County generate annual revenues of $39 million, most of which is from crops. McCook County is the 53rd largest county (576 square miles) in South Dakota. It's located in the Southeast South Dakota region of South Dakota.