There was a combined around $9 million of land and rural real estate for sale in McCook County recently on Land.com. The total size of all McCook County land for sale was approximately 1,000 acres. McCook County ranks 21st out of 66 counties in the state for the total number of acres of land currently advertised for sale. Canistota had the most land for sale. Agriculture and farming drives the McCook County economy, with 568 farms recorded in the county during the U.S. Census in 2012. Farming activities in McCook County generate annual revenues of $39 million, most of which is from crops. McCook County is the 53rd biggest county (576 square miles) in South Dakota. It's located in the Southeast South Dakota region of South Dakota.