There was a combined $9 million of land and rural real estate for sale in McCook County, South Dakota, recently on Land.com. The total of all McCook County farms, ranches, hunting land and other land for sale was almost 1,000 acres. McCook County ranks 22nd out of 66 counties in South Dakota for the total number of acres of land currently advertised for sale. Canistota featured the most land for sale. McCook County has a large agricultural economy, with 568 farms recorded in the county during the latest U.S. Census. Farming activities in McCook County generate annual revenues of $39 million, most of which is from crops. McCook County is the 53rd biggest county (576 square miles) in South Dakota. It's located in the Southeast South Dakota region of South Dakota.